Past Abstracts - Oral Presentations from CAMS 2018 Scientific Conference
INPATIENT PSYCHIATRIC TREATMENT OF CHINESE INTERNATIONAL STUDENTS IN THE US: A CASE REPORT Nadine A. Chang, Ph.D. and Fong Liu, M.D. Gracie Square Hospital, New York-Presbyterian Regional Hospital Network 420 East 76th Street, New York, NY 10021. BACKGROUND: As rates of international students at US universities drop, those from China, comprising one- third of this group, are increasing. The well-documented underutilization of behavioral healthcare services by Asians is similarly reflected in international students, alongside higher rates of mental illness. Contributing factors include language barriers, cultural differences, academic and family pressures and stigma around mental health. In light of several students from China requiring inpatient psychiatric care at the Asian Psychiatry Program at Gracie Square Hospital, we present a case report illustrating challenges faced by behavioral healthcare providers in treating this underserved population.
ASSESSING THE KNOWLEDGE OF THE OSTEOPATHIC PROFESSION IN NEW YORK CITY’S ASIAN COMMUNITIES Justin Chin1*, Sarah Li2, Gregory Yim2, YaQun Zhou2, Peter Wan2, Vincent Dong2, Nathan Kang2, Anisha Rajavel2, Jeremy Shugar DO3, Sonu Sahni MD4, Christine Lomiguen MD5 1. OMS-III, Touro College of Osteopathic Medicine *Corresponding Author: Justin Chin, OMS-III BACKGROUND: Despite having practice privileges in over 50 countries, many immigrant minority communities in the United States are unexposed to osteopathic physicians (DO) prior to re-establishing healthcare in the United States and thus may be reticent to osteopathic manipulative medicine (OMM).
LESSONS LEARNED FROM A QUALITATIVE EVALUATION OF A BILINGUAL PARENT TRAINING FOR CHINESE AMERICAN PARENTS OF CHILDREN WITH SPECIAL HEALTHCARE NEEDS Matthew Chin1,2, BA; Angela Chan1, MD MPH; Sherry Shao Fen Huang1, MD; Naumi Feldman1, DrPH; Xing Li1, MPH; Chun Hui Dong1; Mei Yee Lau1 1Charles B. Wang Community Health Center, 268 Canal Street, New York City, NY 10013 2Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205 BACKGROUND: A federally qualified health center identified significant gaps in culturally and linguistically competent services for Chinese American families of children with special healthcare needs (CSHCN). To address these gaps, the health center worked with a community partner to develop a bilingual applied behavior analysis training for Chinese speaking parents, teaching techniques for developing and maintaining positive behavior. An evaluation of this training was performed to examine changes parent attitude, knowledge, skills, and stress related to caring for their CSHCN.
DEVELOPMENT OF AN EVIDENCE-BASED TOOLKIT TO IMPROVE ADVANCE CARE PLANNING FOR UNDERSERVED CHINESE-AMERICAN IMMIGRANTS Lara Dhingra, MJHS Innovation in Palliative Care, NY 10006; William Cheung, Community Private Practice, NY 10002; Xiaotian Zhou, Columbia University, NY 10027; Philip Huang, New York University, NY 10003; Jack Chen, MJHS Innovation in Palliative Care, NY 10006; Victor Chang, East Orange Veterans Administration Medical Center, NJ 07018; Mosammath Sultana, Hunter College, NY 10065; and Russell Portenoy, MJHS Innovation in Palliative Care, NY 10027 BACKGROUND: The Chinese-American population is rapidly growing and many are non-English-speaking and medically underserved. Advance care planning (ACP) which allows patients and families to engage in informed shared decision-making through documentation of advance directives that are legal and actionable are highly valued outcomes. However, little is known regarding their preferences for ACP.
SERUM METABOLITES ARE ASSOCIATED WITH ALL-CAUSE MORTALITY IN CHRONIC KIDNEY DISEASE Jiun-Ruey Hu, MD MPH1,2,3, Josef Coresh, MD PhD1,2, Lesley A. Inker, MD MS4, Andrew S. Levey, MD4, Zihe Zheng, MHS1,2, Casey M. Rebholz, PhD MPH MS1,2, Adrienne Tin, PhD1,2, Lawrence J. Appel, MD MPH1,2, Jingsha Chen, MS1,2, Mark J. Sarnak, MD MS4, Morgan E. Grams, MD PhD1,2,5 Author Affiliations:
BACKGROUND: Chronic kidney disease (CKD) has a high mortality rate and significant metabolic abnormalities. The levels of serum metabolites in CKD patients might provide insight into subclinical disease states and risk for future mortality. The aim of this study was to determine which serum metabolites, beyond known markers such as creatinine, reproducibly associate with long-term all-cause mortality in CKD using a rigorous discovery and replication design. (Oral 2) Hu, Ruey CAMS 2018 Metabolome Mortality in CKD Abstract JRH (6-11-2018).docx
BUTYRATE-PRODUCING GUT BACTERIA AND VIRAL INFECTIONS IN KIDNEY TRANSPLANT RECIPIENTS Jennifer Huang1, Matthew Magruder1, Lisa Zhang1, Shady Albakry1, Emmanuel Edusei1, Eric Pamer2, Manikkam Suthanthiran1, John Richard Lee1. 1Weill Cornell Medicine, New York, NY 10021; 2Memorial Sloan Kettering Cancer Center, New York, NY 10065. BACKGROUND: Recent studies suggest that the gut microbiome plays a critical role in protecting its host from infections beyond Clostridium difficile. Notably, butyrate-producing bacteria may be beneficial to gut health and have recently have been associated with lower rates of respiratory tract infections in bone marrow transplant recipients (Haak et al., Blood 131(26): 2978, 2018). In this study, we evaluated the relationship between butyrate- producing gut bacteria and future development of viral infections in kidney transplant recipients.
DEVELOPMENT AND VISUAL ASSESSMENT OF A DEEP LEARNING SYSTEM FOR AUTOMATED TUBERCULOSIS SCREENING Tae Kyung Kim, BA, Paul H Yi, MD, Gregory Hager, PhD, Cheng Ting Lin, MD. Radiology Artificial Intelligence Laboratory, Johns Hopkins University School of Medicine. BACKGROUND: Tuberculosis (TB) is one of the top 10 causes of death worldwide, with particularly high disease burden in China, which reports 1 million new cases of TB annually. Screening efforts amongst Chinese patients have been limited partially due to barriers to healthcare access, which could be addressed via automated chest radiograph (CXR) screening methods utilizing deep learning. The purpose of this study was to develop and test the performance of a deep convolutional neural network (DCNN) for the automated detection of tuberculosis on CXRs. (Poster 2) Kim, Tony (Abstract Final V2).docx
IMPORTANCE OF HIV SCREENING AND ACCESS TO PRIMARY CARE IN IMMIGRANT POPULATION Htet Htet Kyaw, MD 2, Myat Kyaw Ko, MD 2, Shwe Sin Phyo2, Zeyar Thet, MD 1, 2 Corresponding author: Zeyar Thet, Kings County Infectious Disease PC, 133-24 Sanford Ave, #1K, Flushing, NY 11355 BACKGROUND: Currently, no data were available for HIV status in immigrant Asian population, especially for Chinese. We hypothesized that intravenous drug users were not so common as other population and data for the prevalence of HIV in immigrants were lacking. This study was to look for the prevalence of HIV status in the immigrant population in relation to age, sex, race and mode of transmission. (Oral 4) Kyaw, Htet Htet 10-24-2018.docx
A CASE OF BILATERAL SCLERITIS AFTER ZOLEDRONATE INFUSION Lisa Kiu Law, M.D.* INTRODUCTION: Bisphosponates are a commonly-used class of medications to prevent bone density loss. As such, they are often used in the treatment of osteoporosis, Paget’s disease, and similar bone diseases. Intravenous bisphosphonate regimens, such as zoledronate (zoledronic acid), have the benefit of less-frequent dosing compared to oral agents, and can be dosed annually. We report a case of 68 year-old male who developed severe bilateral ocular inflammation, including scleritis, anterior uveitis with unilateral fibrinous hypopyon and corneal decompensation, 4 days after his first zoledronate infusion. (Print Only 2) Law, Lisa A CASE OF BILATERAL SCLERITIS AFTER ZOLEDRONATE INFUSION (10-23-2018).docx
EFFECTIVENESS OF QUIET REST COMPARED TO SLEEP IN RESTORING NEURONS FATIGUED BY INTENSIVE LEARNING TASKS Nancy Lin, Serena Ricci, Elisa Tatti, Aaron Nelson, and M. Felice Ghilardi. City University of New York School of Medicine, 160 Convent Avenue, New York City, New York 10031. BACKGROUND: Local sleep is a phenomenon that occurs when fatigued neurons undergo slow wave sleep in a region of the brain while the organism is still awake. This study looks at whether periods of quiet rest are as effective as napping in reducing neuronal fatigue in humans.
PRELIMINARY RESULTS ON META-ANALYSIS OF MRCC METASTATIC DISTRIBUTION OVER TIME Justin Lin *1; Che-Kai Tsao, MD *2. *1 CUNY School of Medicine, 160 Convent Avenue, New York, NY 10031. *2 The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Place, New York, NY 10029 BACKGROUND: Treatment and detection of metastatic renal cell carcinoma (mRCC) has undergone a renaissance in the past few decades, drastically increasing the 5-year survival rates. Therapeutic advances in other malignancies such as breast cancer and prostate cancer have resulted in an alteration in the natural history of the disease. We examined the trend of metastatic site distribution in mRCC patients over the course of the past 3 decades (1990-2018) to evaluate whether a new pattern of metastasis has emerged for mRCC. (Poster 3) Lin Justin - CAMS Abstract 083118.doc
A SINGLE CENTER EXPERIENCE OF CHRONIC HEPATITIS B INFECTION AMONG PEDIATRIC CHINESE POPULATION IN THE UNITED STATES Shirley Mo1,2, Loretta Au, MD, MPH2, Sherry Huang, MD2, Preeti Malik, MBBS, MPH3, Debra H. Pan, MD3 1CUNY School of Medicine, 160 Convent Avenue, Convent Ave, New York, NY 10031 2Charles B. Wang Community Health Center, 125 Walker St, New York, NY 10013 3The Children’s Hospital at Montefiore, 3415 Bainbridge Avenue, Bronx, NY 10467 BACKGROUND: Asian Americans comprise less than 5% of the total population in the US, but account for more than 50% of the nearly 1 million Americans with chronic hepatitis B virus (HBV) infection. There are few studies on the natural history of HBV infection in Asian American children. (Oral 6) Shirley Mo_2018 CAMS Research Fellowship Abstract (10-24-2018).docx
IMPROVING MATERNAL DEPRESSION SCREENING WITH A SMARTPHONE APPLICATION IN A VULNERABLE POPULATION: PRELIMINARY RESULTS Tram N.B. Nguyen, BS1; Sarah Ricketts, MD2; Henry Chung, MD1,2
BACKGROUND: The depression rate during and after pregnancy is approximately 7 – 12.7% and likely higher in low income and minority populations. Maternal depression has been associated with fewer and later prenatal visits, preterm birth, low birth weight, intrauterine growth restriction, and preeclampsia. However, rates of peripartum screening for depression remain low in clinical practice. To address this problem, we piloted a patient-centered, HIPAA compliant smartphone application at two Montefiore OB clinics located in the Bronx to facilitate periodic screening for mood, substance use, and psychosocial stressors. The app also delivers medically accurate patient education materials throughout pregnancy, and patients can use the chat feature to communicate with the healthcare team.
THE ROLE OF FCGR2B IN REGULATING AUTOREACTIVE PLASMA CELLS IN LUPUS Gabriella Schmuter *1,2, Jolien Suurmond PhD *1, Betty Diamond MD *1 BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease in which the body’s immune system attacks healthy tissue. There is currently no cure for SLE. A mutation in the gene Fcgr2b has been associated with lupus in humans. The exact mechanism of Fcgr2b in the regulation of autoantibodies in SLE is currently unclear. The purpose of the current study is to examine the role of Fcgr2b in its regulation of autoreactive plasma cells.
SERUM LONG NONCODING RNA HOTAIR AS NOVEL DIAGNOSTIC AND PROGNOSTIC BIOMARKER IN GLIOBLASTOMA MULTIFORME Sze Kiat Tan1,2, Chiara Pastori1, Clara Penas2, Ricardo J. Komotar1, Michael E. Ivan1, Claes Wahlestedt3, Nagi G. Ayad2 1 Department of Neurosurgery, Sylvester Comprehensive Cancer Center, University of Miami Brain Tumor Initiative, University of Miami Miller School of Medicine, Miami, Florida, 33136. 2 Center for Therapeutic Innovation, Miami Project to Cure Paralysis, Sylvester Comprehensive Cancer Center, University of Miami Brain Tumor Initiative, Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, Florida, 33136. 3 Center for Therapeutic Innovation, Sylvester Comprehensive Cancer Center, University of Miami Brain Tumor Initiative, Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, Florida, 33136. BACKGROUND: Glioblastoma multiforme (GBM) is the most common malignant adult brain tumor. Therefore, there is an urgent need to develop a peripheral biomarker for GBM. Long noncoding RNAs (lncRNAs) have emerged as new players in cancer paradigm, demonstrating potential roles in both oncogenic and tumor- suppressive pathways. Utilizing single molecule sequencing, we have previously demonstrated that hundreds of lncRNAs, including HOTAIR, are strongly dysregulated in GBM and HOTAIR is critical in GBM cells proliferation. The purpose of this study was to investigate the prognostic and diagnostic values of serum HOTAIR in GBM. (Poster 6) Tan, Sze Kiat (8-3-2018).docx
CORRELATION OF STEADY-STATE PATTERN ELECTRORETINOGRAM AND HUMPHREY VISUAL FIELD IN GLAUCOMA SUSPECT PATIENTS Benny Yiu Wong1, Andrew Tirsi MD1, Jung M Lee MD1, Sung Chul Park MD1,2, Celso Tello MD1,2 1Department of Ophthalmology, Manhattan Eye, Ear & Throat Hospital, New York, NY Manhattan Eye, Ear & Throat Hospital 210 East 64th St New York, NY 10065 BACKGROUND: Glaucoma is the second leading cause of blindness worldwide. The evaluation of the visual pathway relies on the subjective visual field (VF) assessment. Studies have shown that in early glaucoma, up to 35% of retinal ganglion cells are lost before the first visual field defects manifest. The subjective nature of VF administration and the necessity of implementing a new diagnostic test of the absolute beginning of glaucomatous damage have led to a growing interest in alternative, objective information provided by electrophysiological studies. Electrophysiological techniques can play a valuable complementary role in the screening of early glaucoma in an objective functional manner. The purpose of this study was to assess the relationship between Humphrey visual field values (HVF) and steady-state pattern electroretinography parameters (PERG) in glaucoma suspects. (Print Only 4) Wong, Benny_Abstract_Submission_1 (10-23-2018).docx
A PILOT STUDY COMPARISON OF SCOTOPIC PUPIL SIZE USING THE COLVARD PUPILLOMETER AND THE MEIBOX INFRARED MEIBOGRAPHER. Sarah Wu1, Nicole Lemanski2, Brian Lemanski2,3 1NYU College of Arts & Sciences, New York, NY 10003. 2Mabel MP Cheng MD, PLLC, Niskayuna, NY 12309.3Applied Imaging Technologies, Schenectady, NY 12309. BACKGROUND: Scotopic (dark adapted) pupil measurements are important for determining surgical candidacy for LASIK/PRK or presbyopia correcting intraocular lenses. Larger scotopic pupils are correlated with visual side effects, including halos, starbursts and glare. The Colvard pupillometer (CP) is the gold standard method of pupillometry. However, the device lacks image capture and is subject to test/retest variability. Previous studies have demonstrated the potential of infrared cameras to obtain accurate and reproducible measurements. This study investigated the accuracy and reproducibility of the Meibox infrared Meibographer (Box Medical Solutions) , against the Colvard Pupillometer (Oasis Medical Inc).
IDENTIFICATION OF PATIENT AND HEALTH SYSTEM FACTORS RELATED TO EARLY AND LATE PRESENTATIONS OF BREAST CANCER IN TANZANIA Kristen Yang, City University of New York School of Medicine, 160 Convent Avenue 10031 Khadija Msami, Ocean Road Cancer Institute, Dar es Salaam, Tanzania BACKGROUND: Breast cancer is the most common cancer among women worldwide, and is fatal for over 56% of diagnosed Tanzanian women because of the lack of the breast cancer screening and attendance. The purpose of this study was to identify patient and health system factors that predict the presentations of early or late stages of breast cancer among female patients at the Ocean Road Cancer Institute (ORCI) in Dar es Salaam, Tanzania.
UNDERSTANDING CAUSES OF LOSS TO FOLLOW-UP AMONG WOMEN SUSPECTED OF CERVICAL LESIONS IN TANZANIA Elizabeth T. Yim, CUNY School of Medicine, NY 10031 BACKGROUND: In Tanzania, cervical cancer is the leading cause of cancer and cancer-related death. The Ocean Road Cancer Institute (ORCI) is regarded as the gold standard for cervical cancer screening due to its resources and experienced screening clinic nurses. In 2015, The World Health Organization (WHO) established a referral program between two local health clinics, Temeke Referral Hospital and Magomeni Health Center, to the Ocean Road Cancer Institute. If nurses observed lesions or symptoms of suspected cervical cancer, patients were referred to Ocean Road. In 2017, a study was published that revealed that from February 2015 to May 2016, 44% of patients referred to the ORCI from Magomeni and 64% of women from Temeke did not go for screening. The aim of this study was to understand the causes of loss to follow up among women referred to ORCI from these health clinics.
CELL FREE DNA ANALYSIS OF PERITONEAL FLUID IS DIAGNOSTIC OF COMMON AND RARE CASES OF PERITONITIS IN PERITONEAL DIALYSIS PATIENTS Lisa Zhang1, Fanny Chen2, Philip Burnham2, Emmanuel Edusei1, Amanda Renaghan1, Susan Guo1, Shady Albakry1, Brittany Botticelli1, Vesh Srivatana3, Jeffrey Silberzweig3, Joshua Hayden1, Lars Westblade1, John Lee1(Research Mentor),1 Iwijn De Vlaminck2 1Weill Cornell, NY 2Cornell University, NY 3 Rogosin Institute NY BACKGROUND: Peritoneal dialysis (PD) is a lifesaving therapy for patients with end stage kidney disease, but peritonitis, a frequent infectious complication, limits its efficacy. Although microbial culture of the peritoneal fluid is currently the definitive diagnostic approach, in 20% of suspected peritonitis cases the causative organism cannot be identified. We investigated the utility of cell free DNA (cfDNA) in peritoneal fluid as an alternative assay to identify pathogens in peritonitis cases. (Poster 9) Zhang, Lisa 10-24-2018.docx
IDENTIFYING MYOSITIS SPECIFIC T-CELL RECEPTOR Xuwen Alice Zheng, Janelle Montagne Iago P. Fernandez, Lisa Christopher-Stine, Thomas E. Lloyd, Andrew L. Mammen, & H. Benjamin Larman BACKGROUND: Every T cell responding to a different antigen has a distinct T cell Receptor (TCR) that recognizes antigen. Since autoimmune diseases arise when T cell recognize “self” proteins as foreign, screening their T cell specificity can reveal how their immune responses differ from healthy individuals. However, accurately determining a T cell’s antigen specificity is a methodologic challenge. We hypothesized that by sequencing T cell receptors, we could reliably match TCR sequence to antigen specificity. To test this, we screened muscle biopsies from patients with different types of myositis. (Print Only 6) Zheng, Alice.docx
ROLE OF CD8+ B CELLS IN ALLOGRAFT REJECTION IN NON-HUMAN PRIMATES Joseph Yi Zhou (1), Jane O (2), Kurt Pruner (2), Joren C. Madsen (2) BACKGROUND: Long-term survival of patients with end-stage organ failure receiving allotransplanted organs such as the heart and lung, is compromised by immune- mediated rejection of the organ. The transmembrane glycoprotein CD8, classically found only in cytotoxic T lymphocytes, has been discovered in a subset of B lymphocytes in the non- human primate (NHP) model. We hypothesized that this novel population of CD8+ B lymphocytes may participate in graft rejection. In order to determine this, we studied CD8+ B lymphocyte signatures in a cohort of non-human primates (NHP) treated with anti-CD8 monoclonal antibody (aCD8 mAB). (Poster 10) Zhou, Joseph Abstract (Revised v2 FINAL).docx
|
|
|
|
|
|
